GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THYM | cis | rs2239557 | 1 | rs10140433 | chr14:74659989 | LIN52 | chr14:74551656-74667117:+ | -0.39 | -7.22 | 1.25E-10 | Common traits (Other) |
| THYM | cis | rs2239557 | 1 | rs10144220 | chr14:74647904 | LIN52 | chr14:74551656-74667117:+ | -0.39 | -7.16 | 1.73E-10 | Common traits (Other) |
| THYM | cis | rs2239557 | 1 | rs10150201 | chr14:74649157 | LIN52 | chr14:74551656-74667117:+ | -0.39 | -7.16 | 1.73E-10 | Common traits (Other) |
| THYM | cis | rs4660306 | 1 | rs10157597 | chr1:45990278 | CCDC163P | chr1:45960581-45965646:- | -0.85 | -14.31 | 1.95E-25 | Homocysteine levels |
| THYM | cis | rs9815354 | 1 | rs1016669 | chr3:41894440 | ULK4 | chr3:41288091-42003660:- | 1.02 | 11.47 | 1.22E-19 | Diastolic blood pressure |
| THYM | cis | rs3820928 | 1 | rs10167422 | chr2:227777554 | RHBDD1 | chr2:227700773-227861591:+ | -0.31 | -4.54 | 1.67E-5 | Pulmonary function |
| THYM | cis | rs9309473 | 1 | rs10169714 | chr2:73808773 | ALMS1P | chr2:73872046-73912692:+ | 0.59 | 4.53 | 1.69E-5 | Metabolite levels |
| THYM | cis | rs9309473 | 1 | rs10175180 | chr2:73673123 | ALMS1P | chr2:73872046-73912692:+ | 0.58 | 4.72 | 8.0E-6 | Metabolite levels |
| THYM | cis | rs10178409 | 1 | rs10178409 | chr2:73855507 | ALMS1P | chr2:73872046-73912692:+ | 0.66 | 4.97 | 2.93E-6 | Urinary metabolites |
| THYM | cis | rs9309473 | 1 | rs10179134 | chr2:73637519 | ALMS1P | chr2:73872046-73912692:+ | 0.58 | 4.3 | 4.1E-5 | Metabolite levels |
| THYM | cis | rs1577917 | 1 | rs1018184 | chr6:86648475 | SNHG5 | chr6:86386726-86388451:- | 0.57 | 6.85 | 7.2E-10 | Response to antipsychotic treatment |
| THYM | cis | rs9309473 | 1 | rs10184268 | chr2:73627044 | ALMS1P | chr2:73872046-73912692:+ | 0.57 | 4.51 | 1.85E-5 | Metabolite levels |
| THYM | cis | rs9309473 | 1 | rs10186501 | chr2:73697844 | ALMS1P | chr2:73872046-73912692:+ | 0.58 | 4.72 | 8.0E-6 | Metabolite levels |
| THYM | cis | rs9309473 | 1 | rs10187192 | chr2:73713500 | ALMS1P | chr2:73872046-73912692:+ | 0.63 | 4.71 | 8.5E-6 | Metabolite levels |
| THYM | cis | rs9309473 | 1 | rs10187416 | chr2:73713741 | ALMS1P | chr2:73872046-73912692:+ | 0.57 | 4.73 | 7.87E-6 | Metabolite levels |